Synthesis of lipophilic N 9-benzylguanine derivatives

Jeremy E.B. McCallum; Kenneth G. Huston; Jacqueline M. McSweeney; Brandie G. Rucker

doi:10.1055/s-0030-1259037

Synthesis of lipophilic N ⁹-benzylguanine derivatives

Jeremy E.B. McCallum
, Kenneth G. Huston
, Jacqueline M. McSweeney
, Brandie G. Rucker

Office of the Dean SOMAS

Loyola Marymount University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Lipophilic N⁹-benzylguanine derivatives were synthesized from the arylalkylation of 2-N-acetylguanine with substituted benzyl bromides.

Original language	English
Pages (from-to)	2871-2874
Number of pages	4
Journal	Synlett
Issue number	19
DOIs	https://doi.org/10.1055/s-0030-1259037
State	Published - 2010

Keywords

2-N-acetylguanine
benzylation
HMBC
nucleobases
regio-selectivity

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@article{27020ed61e7c41f0b6ea97f51ffe88eb,

title = "Synthesis of lipophilic N 9-benzylguanine derivatives",

abstract = "Lipophilic N9-benzylguanine derivatives were synthesized from the arylalkylation of 2-N-acetylguanine with substituted benzyl bromides.",

keywords = "2-N-acetylguanine, benzylation, HMBC, nucleobases, regio-selectivity",

author = "McCallum, \{Jeremy E.B.\} and Huston, \{Kenneth G.\} and McSweeney, \{Jacqueline M.\} and Rucker, \{Brandie G.\}",

year = "2010",

doi = "10.1055/s-0030-1259037",

language = "English",

pages = "2871--2874",

journal = "Synlett",

issn = "0936-5214",

number = "19",

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TY - JOUR

T1 - Synthesis of lipophilic N 9-benzylguanine derivatives

AU - McCallum, Jeremy E.B.

AU - Huston, Kenneth G.

AU - McSweeney, Jacqueline M.

AU - Rucker, Brandie G.

PY - 2010

Y1 - 2010

N2 - Lipophilic N9-benzylguanine derivatives were synthesized from the arylalkylation of 2-N-acetylguanine with substituted benzyl bromides.

AB - Lipophilic N9-benzylguanine derivatives were synthesized from the arylalkylation of 2-N-acetylguanine with substituted benzyl bromides.

KW - 2-N-acetylguanine

KW - benzylation

KW - HMBC

KW - nucleobases

KW - regio-selectivity

UR - https://www.scopus.com/pages/publications/78650180372

U2 - 10.1055/s-0030-1259037

DO - 10.1055/s-0030-1259037

M3 - Article

AN - SCOPUS:78650180372

SN - 0936-5214

SP - 2871

EP - 2874

JO - Synlett

JF - Synlett

IS - 19

ER -

Synthesis of lipophilic N ⁹-benzylguanine derivatives

Abstract

Keywords

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