Synthetic riboswitches that induce gene expression in diverse bacterial species

Shana Topp; Colleen M.K. Reynoso; Jessica C. Seeliger; Ian S. Goldlust; Shawn K. Desai; Dorothée Murat; Aimee Shen; Aaron W. Puri; Arash Komeili; Carolyn R. Bertozzi; June R. Scott; Justin P. Gallivan

doi:10.1128/AEM.01537-10

Synthetic riboswitches that induce gene expression in diverse bacterial species

Shana Topp
, Colleen M.K. Reynoso
, Jessica C. Seeliger
, Ian S. Goldlust
, Shawn K. Desai
, Dorothée Murat
, Aimee Shen
, Aaron W. Puri
, Arash Komeili
, Carolyn R. Bertozzi
, June R. Scott
, Justin P. Gallivan

Emory University
University of California at Berkeley
Stanford University

Research output: Contribution to journal › Article › peer-review

181 Scopus citations

Abstract

We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We anticipate that these riboswitches will be useful tools for genetic studies in a wide range of bacteria.

Original language	English
Pages (from-to)	7881-7884
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	76
Issue number	23
DOIs	https://doi.org/10.1128/AEM.01537-10
State	Published - Dec 2010

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title = "Synthetic riboswitches that induce gene expression in diverse bacterial species",

abstract = "We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We anticipate that these riboswitches will be useful tools for genetic studies in a wide range of bacteria.",

author = "Shana Topp and Reynoso, \{Colleen M.K.\} and Seeliger, \{Jessica C.\} and Goldlust, \{Ian S.\} and Desai, \{Shawn K.\} and Doroth{\'e}e Murat and Aimee Shen and Puri, \{Aaron W.\} and Arash Komeili and Bertozzi, \{Carolyn R.\} and Scott, \{June R.\} and Gallivan, \{Justin P.\}",

year = "2010",

month = dec,

doi = "10.1128/AEM.01537-10",

language = "English",

volume = "76",

pages = "7881--7884",

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T1 - Synthetic riboswitches that induce gene expression in diverse bacterial species

AU - Topp, Shana

AU - Reynoso, Colleen M.K.

AU - Seeliger, Jessica C.

AU - Goldlust, Ian S.

AU - Desai, Shawn K.

AU - Murat, Dorothée

AU - Shen, Aimee

AU - Puri, Aaron W.

AU - Komeili, Arash

AU - Bertozzi, Carolyn R.

AU - Scott, June R.

AU - Gallivan, Justin P.

PY - 2010/12

Y1 - 2010/12

N2 - We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We anticipate that these riboswitches will be useful tools for genetic studies in a wide range of bacteria.

AB - We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We anticipate that these riboswitches will be useful tools for genetic studies in a wide range of bacteria.

UR - https://www.scopus.com/pages/publications/78650368337

U2 - 10.1128/AEM.01537-10

DO - 10.1128/AEM.01537-10

M3 - Article

C2 - 20935124

AN - SCOPUS:78650368337

SN - 0099-2240

VL - 76

SP - 7881

EP - 7884

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 23

ER -

Synthetic riboswitches that induce gene expression in diverse bacterial species

Abstract

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