System performance simulations of the RatCAP awake rat brain scanner

Sepideh Shokouhi; Paul Vaska; David J. Schlyer; Scan P. Stoll; Azael Villanueva; Aarti Kriplani; Craig L. Woody

doi:10.1109/TNS.2005.858236

System performance simulations of the RatCAP awake rat brain scanner

Sepideh Shokouhi
, Paul Vaska
, David J. Schlyer
, Scan P. Stoll
, Azael Villanueva
, Aarti Kriplani
, Craig L. Woody

Dept of Biomedical Engineering

IEEE
Stony Brook University
Brookhaven National Laboratory

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The capability to create high quality images from data acquired by the Rat Conscious Animal PET tomograph (RatCAP) has been evaluated using modified versions of the PET Monte Carlo code Simulation System for Emission Tomography (SimSET). The proposed tomograph consists of lutetium oxyorthosilicate (LSO) crystals arranged in 12 4 × 8 blocks. The effects of the RatCAPs small ring diameter (∼40 mm) and its block detector geometry on image quality for small animal studies have been investigated. Since the field of view will be almost as large as the ring diameter, radial elongation artifacts due to parallax error are expected to degrade the spatial resolution and thus the image quality at the edge of the field of view. In addition to Monte Carlo simulations, some preliminary results of experimentally acquired images in both two-dimensional (2-D) and 3-D modes are presented.

Original language	English
Pages (from-to)	1305-1310
Number of pages	6
Journal	IEEE Transactions on Nuclear Science
Volume	52
Issue number	5 I
DOIs	https://doi.org/10.1109/TNS.2005.858236
State	Published - Oct 2005

Keywords

SimSET
Small animal imaging

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10.1109/TNS.2005.858236

Cite this

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title = "System performance simulations of the RatCAP awake rat brain scanner",

abstract = "The capability to create high quality images from data acquired by the Rat Conscious Animal PET tomograph (RatCAP) has been evaluated using modified versions of the PET Monte Carlo code Simulation System for Emission Tomography (SimSET). The proposed tomograph consists of lutetium oxyorthosilicate (LSO) crystals arranged in 12 4 × 8 blocks. The effects of the RatCAPs small ring diameter (∼40 mm) and its block detector geometry on image quality for small animal studies have been investigated. Since the field of view will be almost as large as the ring diameter, radial elongation artifacts due to parallax error are expected to degrade the spatial resolution and thus the image quality at the edge of the field of view. In addition to Monte Carlo simulations, some preliminary results of experimentally acquired images in both two-dimensional (2-D) and 3-D modes are presented.",

keywords = "SimSET, Small animal imaging",

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year = "2005",

month = oct,

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pages = "1305--1310",

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AU - Shokouhi, Sepideh

AU - Vaska, Paul

AU - Schlyer, David J.

AU - Stoll, Scan P.

AU - Villanueva, Azael

AU - Kriplani, Aarti

AU - Woody, Craig L.

PY - 2005/10

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N2 - The capability to create high quality images from data acquired by the Rat Conscious Animal PET tomograph (RatCAP) has been evaluated using modified versions of the PET Monte Carlo code Simulation System for Emission Tomography (SimSET). The proposed tomograph consists of lutetium oxyorthosilicate (LSO) crystals arranged in 12 4 × 8 blocks. The effects of the RatCAPs small ring diameter (∼40 mm) and its block detector geometry on image quality for small animal studies have been investigated. Since the field of view will be almost as large as the ring diameter, radial elongation artifacts due to parallax error are expected to degrade the spatial resolution and thus the image quality at the edge of the field of view. In addition to Monte Carlo simulations, some preliminary results of experimentally acquired images in both two-dimensional (2-D) and 3-D modes are presented.

AB - The capability to create high quality images from data acquired by the Rat Conscious Animal PET tomograph (RatCAP) has been evaluated using modified versions of the PET Monte Carlo code Simulation System for Emission Tomography (SimSET). The proposed tomograph consists of lutetium oxyorthosilicate (LSO) crystals arranged in 12 4 × 8 blocks. The effects of the RatCAPs small ring diameter (∼40 mm) and its block detector geometry on image quality for small animal studies have been investigated. Since the field of view will be almost as large as the ring diameter, radial elongation artifacts due to parallax error are expected to degrade the spatial resolution and thus the image quality at the edge of the field of view. In addition to Monte Carlo simulations, some preliminary results of experimentally acquired images in both two-dimensional (2-D) and 3-D modes are presented.

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KW - Small animal imaging

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M3 - Article

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JO - IEEE Transactions on Nuclear Science

JF - IEEE Transactions on Nuclear Science

IS - 5 I

ER -

System performance simulations of the RatCAP awake rat brain scanner

Abstract

Keywords

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