T cells target TB

Atul Pradhan; Charles Kyriakos Vorkas

doi:10.1016/j.chom.2023.02.003

T cells target TB

Atul Pradhan
, Charles Kyriakos Vorkas

Infectious Diseases

Stony Brook University

Research output: Contribution to journal › Comment/debate

1 Scopus citations

Abstract

Recently in Nature Medicine, Musvosvi et al. analyzed single-cell T cell receptor (TCR) sequencing by grouping of lymphocyte interactions by paratope hotspots (GLIPH2) in a South African longitudinal cohort at high risk for tuberculosis. They find peptide antigen-specific T cells correlating with control of primary infection, potentially informing future vaccines.

Original language	English
Pages (from-to)	329-330
Number of pages	2
Journal	Cell Host and Microbe
Volume	31
Issue number	3
DOIs	https://doi.org/10.1016/j.chom.2023.02.003
State	Published - Mar 8 2023

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10.1016/j.chom.2023.02.003

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title = "T cells target TB",

abstract = "Recently in Nature Medicine, Musvosvi et al. analyzed single-cell T cell receptor (TCR) sequencing by grouping of lymphocyte interactions by paratope hotspots (GLIPH2) in a South African longitudinal cohort at high risk for tuberculosis. They find peptide antigen-specific T cells correlating with control of primary infection, potentially informing future vaccines.",

author = "Atul Pradhan and Vorkas, \{Charles Kyriakos\}",

note = "Publisher Copyright: {\textcopyright} 2023",

year = "2023",

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T1 - T cells target TB

AU - Pradhan, Atul

AU - Vorkas, Charles Kyriakos

PY - 2023/3/8

Y1 - 2023/3/8

N2 - Recently in Nature Medicine, Musvosvi et al. analyzed single-cell T cell receptor (TCR) sequencing by grouping of lymphocyte interactions by paratope hotspots (GLIPH2) in a South African longitudinal cohort at high risk for tuberculosis. They find peptide antigen-specific T cells correlating with control of primary infection, potentially informing future vaccines.

AB - Recently in Nature Medicine, Musvosvi et al. analyzed single-cell T cell receptor (TCR) sequencing by grouping of lymphocyte interactions by paratope hotspots (GLIPH2) in a South African longitudinal cohort at high risk for tuberculosis. They find peptide antigen-specific T cells correlating with control of primary infection, potentially informing future vaccines.

UR - https://www.scopus.com/pages/publications/85149699792

U2 - 10.1016/j.chom.2023.02.003

DO - 10.1016/j.chom.2023.02.003

M3 - Comment/debate

C2 - 36893731

AN - SCOPUS:85149699792

SN - 1931-3128

VL - 31

SP - 329

EP - 330

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 3

ER -

T cells target TB

Abstract

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