Abstract
Lacking ongoing genomic DNA transcription, platelets represent a unique model system for studying interactions between transcriptome and proteome. This chapter focuses on application of comparative transcriptomic studies for predicting novel proteins and pathways in platelets and for identification of molecular signatures of platelet-related disorders. In the future, integration of transcript and protein profiling approaches will permit the identification of molecular mechanisms of platelet function at a new level.
| Original language | English |
|---|---|
| Title of host publication | Platelet Proteomics |
| Subtitle of host publication | Principles, Analysis, and Applications |
| Publisher | John Wiley and Sons |
| Pages | 231-251 |
| Number of pages | 21 |
| ISBN (Print) | 9780470463376 |
| DOIs | |
| State | Published - Jul 12 2011 |
Keywords
- Microarray analysis application, and proteomics - platelet-associated disorders, genes and proteins
- Ongoing genomic DNA transcription lack - platelet, model system for transcriptome-proteome interaction study
- Platelet transcriptome in normal state, disease - genomewide transcript profiling, molecular signatures of platelet-associated diseases
Fingerprint
Dive into the research topics of 'The Application of Microarray Analysis and its Integration with Proteomics for Study of Platelet-Associated Disorders'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver