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The effect of cholinergic antagonists on a central response to nicotine

  • University of Rochester

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Mecamylamine and hexamethonium antagonize the prostration response of rats to centrally-administered nicotine; decamethonium and d-tubocurarine are less effective. Physostigmine does not elicit the response. Nicotine's central cholinergic effect thus may contribute to but does not fully account for its action.

Original languageEnglish
Pages (from-to)119-120
Number of pages2
JournalCellular and Molecular Life Sciences
Volume38
Issue number1
DOIs
StatePublished - Jan 1982

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