The emergence of networks in human genome epidemiology: Challenges and opportunities

Daniela Seminara; Muin J. Khoury; Thomas R. O'brien; Teri Manolio; Marta Gwinn; Julian Little; Julian P.T. Higgins; Jonine L. Bernstein; Paolo Boffetta; Melissa L. Bondy; Molly S. Bray; Paul E. Brenchley; Patricia A. Buffler; Juan Pablo Casas; Anand P. Chokkalingam; John Danesh; George Davey Smith; Siobhan M. Dolan; Ross Duncan; Nelleke A. Gruis; Mia Hashibe; David J. Hunter; Marjo Riitta Jarvelin; Beatrice Malmer; Demetrius M. Maraganore; Julia A. Newton-Bishop; Elio Riboli; Georgia Salanti; Emanuela Taioli; Nic Timpson; André G. Uitterlinden; Paolo Vineis; Nick Wareham; Deborah M. Winn; Ron Zimmern; John P.A. Ioannidis

doi:10.1093/acprof:oso/9780195398441.003.0007

The emergence of networks in human genome epidemiology: Challenges and opportunities

Daniela Seminara
, Muin J. Khoury
, Thomas R. O'brien
, Teri Manolio
, Marta Gwinn
, Julian Little
, Julian P.T. Higgins
, Jonine L. Bernstein
, Paolo Boffetta
, Melissa L. Bondy
, Molly S. Bray
, Paul E. Brenchley
, Patricia A. Buffler
, Juan Pablo Casas
, Anand P. Chokkalingam
, John Danesh
, George Davey Smith
, Siobhan M. Dolan
, Ross Duncan
, Nelleke A. Gruis

Mia Hashibe, David J. Hunter, Marjo Riitta Jarvelin, Beatrice Malmer, Demetrius M. Maraganore, Julia A. Newton-Bishop, Elio Riboli, Georgia Salanti, Emanuela Taioli, Nic Timpson, André G. Uitterlinden, Paolo Vineis, Nick Wareham, Deborah M. Winn, Ron Zimmern, John P.A. Ioannidis

Family , Population and Preventative Medicine

National Institutes of Health
Centers for Disease Control and Prevention
University of Ottawa
University of Cambridge
Memorial Sloan-Kettering Cancer Center
University of Texas System
University of Texas MD Anderson Cancer Center
University of Texas Health Science Center at Houston
Manchester University NHS Foundation Trust
University of California at Berkeley
London School of Hygiene and Tropical Medicine
University of Bristol
Albert Einstein College of Medicine
Leiden University
Harvard University
International Agency for Research on Cancer
Imperial College London
University of Oulu
Umeå University
Mayo Clinic Rochester, MN
CR-UK Clinical Centre
Foundation for Research and Technology-Hellas
University of Pittsburgh
Erasmus University Rotterdam
MRC Epidemiology Unit
PHG Foundation
School of Medicine and Biomedical Research Institute
University of Ioannina
Tufts University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The Human Genome Epidemiology Network (HuGENet) recently launched a global network of consortia working on human genome epidemiology. This Network of Investigator Networks aims to create a resource to share information, offer methodologic support, generate inclusive overviews of studies conducted in specific fields, and to facilitate rapid confirmation of findings. In October 2005, HuGENet brought together representatives from established and emerging networks in order to share their experiences at a workshop in Cambridge, United Kingdom. In advance of the meeting, a qualitative questionnaire was distributed to workshop participants. The questionnaire elicited information on experiences and practices in building and maintaining consortia. This chapter reports on the numerous challenges and their possible solutions as identified by the workshop participants, as well as new opportunities offered by the network approach to genetic and genomic epidemiology.

Original language	English
Title of host publication	Human Genome Epidemiology
Subtitle of host publication	Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition
Publisher	Oxford University Press
ISBN (Electronic)	9780199776023
ISBN (Print)	9780195398441
DOIs	https://doi.org/10.1093/acprof:oso/9780195398441.003.0007
State	Published - May 1 2010

Keywords

Genetic epidemiology
Hugenet
Human genome epidemiology
Investigator networks

Access to Document

10.1093/acprof:oso/9780195398441.003.0007

Cite this

Seminara, D., Khoury, M. J., O'brien, T. R., Manolio, T., Gwinn, M., Little, J., Higgins, J. P. T., Bernstein, J. L., Boffetta, P., Bondy, M. L., Bray, M. S., Brenchley, P. E., Buffler, P. A., Casas, J. P., Chokkalingam, A. P., Danesh, J., Smith, G. D., Dolan, S. M., Duncan, R., ... Ioannidis, J. P. A. (2010). The emergence of networks in human genome epidemiology: Challenges and opportunities. In Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition Oxford University Press. https://doi.org/10.1093/acprof:oso/9780195398441.003.0007

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title = "The emergence of networks in human genome epidemiology: Challenges and opportunities",

abstract = "The Human Genome Epidemiology Network (HuGENet) recently launched a global network of consortia working on human genome epidemiology. This Network of Investigator Networks aims to create a resource to share information, offer methodologic support, generate inclusive overviews of studies conducted in specific fields, and to facilitate rapid confirmation of findings. In October 2005, HuGENet brought together representatives from established and emerging networks in order to share their experiences at a workshop in Cambridge, United Kingdom. In advance of the meeting, a qualitative questionnaire was distributed to workshop participants. The questionnaire elicited information on experiences and practices in building and maintaining consortia. This chapter reports on the numerous challenges and their possible solutions as identified by the workshop participants, as well as new opportunities offered by the network approach to genetic and genomic epidemiology.",

keywords = "Genetic epidemiology, Hugenet, Human genome epidemiology, Investigator networks",

author = "Daniela Seminara and Khoury, \{Muin J.\} and O'brien, \{Thomas R.\} and Teri Manolio and Marta Gwinn and Julian Little and Higgins, \{Julian P.T.\} and Bernstein, \{Jonine L.\} and Paolo Boffetta and Bondy, \{Melissa L.\} and Bray, \{Molly S.\} and Brenchley, \{Paul E.\} and Buffler, \{Patricia A.\} and Casas, \{Juan Pablo\} and Chokkalingam, \{Anand P.\} and John Danesh and Smith, \{George Davey\} and Dolan, \{Siobhan M.\} and Ross Duncan and Gruis, \{Nelleke A.\} and Mia Hashibe and Hunter, \{David J.\} and Jarvelin, \{Marjo Riitta\} and Beatrice Malmer and Maraganore, \{Demetrius M.\} and Newton-Bishop, \{Julia A.\} and Elio Riboli and Georgia Salanti and Emanuela Taioli and Nic Timpson and Uitterlinden, \{Andr{\'e} G.\} and Paolo Vineis and Nick Wareham and Winn, \{Deborah M.\} and Ron Zimmern and Ioannidis, \{John P.A.\}",

note = "Publisher Copyright: {\textcopyright} Oxford University Press, 2014.",

year = "2010",

month = may,

day = "1",

doi = "10.1093/acprof:oso/9780195398441.003.0007",

language = "English",

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booktitle = "Human Genome Epidemiology",

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Seminara, D, Khoury, MJ, O'brien, TR, Manolio, T, Gwinn, M, Little, J, Higgins, JPT, Bernstein, JL, Boffetta, P, Bondy, ML, Bray, MS, Brenchley, PE, Buffler, PA, Casas, JP, Chokkalingam, AP, Danesh, J, Smith, GD, Dolan, SM, Duncan, R, Gruis, NA, Hashibe, M, Hunter, DJ, Jarvelin, MR, Malmer, B, Maraganore, DM, Newton-Bishop, JA, Riboli, E, Salanti, G, Taioli, E, Timpson, N, Uitterlinden, AG, Vineis, P, Wareham, N, Winn, DM, Zimmern, R & Ioannidis, JPA 2010, The emergence of networks in human genome epidemiology: Challenges and opportunities. in Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press. https://doi.org/10.1093/acprof:oso/9780195398441.003.0007

The emergence of networks in human genome epidemiology: Challenges and opportunities. / Seminara, Daniela; Khoury, Muin J.; O'brien, Thomas R. et al.
Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press, 2010.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - The emergence of networks in human genome epidemiology

T2 - Challenges and opportunities

AU - Seminara, Daniela

AU - Khoury, Muin J.

AU - O'brien, Thomas R.

AU - Manolio, Teri

AU - Gwinn, Marta

AU - Little, Julian

AU - Higgins, Julian P.T.

AU - Bernstein, Jonine L.

AU - Boffetta, Paolo

AU - Bondy, Melissa L.

AU - Bray, Molly S.

AU - Brenchley, Paul E.

AU - Buffler, Patricia A.

AU - Casas, Juan Pablo

AU - Chokkalingam, Anand P.

AU - Danesh, John

AU - Smith, George Davey

AU - Dolan, Siobhan M.

AU - Duncan, Ross

AU - Gruis, Nelleke A.

AU - Hashibe, Mia

AU - Hunter, David J.

AU - Jarvelin, Marjo Riitta

AU - Malmer, Beatrice

AU - Maraganore, Demetrius M.

AU - Newton-Bishop, Julia A.

AU - Riboli, Elio

AU - Salanti, Georgia

AU - Taioli, Emanuela

AU - Timpson, Nic

AU - Uitterlinden, André G.

AU - Vineis, Paolo

AU - Wareham, Nick

AU - Winn, Deborah M.

AU - Zimmern, Ron

AU - Ioannidis, John P.A.

PY - 2010/5/1

Y1 - 2010/5/1

N2 - The Human Genome Epidemiology Network (HuGENet) recently launched a global network of consortia working on human genome epidemiology. This Network of Investigator Networks aims to create a resource to share information, offer methodologic support, generate inclusive overviews of studies conducted in specific fields, and to facilitate rapid confirmation of findings. In October 2005, HuGENet brought together representatives from established and emerging networks in order to share their experiences at a workshop in Cambridge, United Kingdom. In advance of the meeting, a qualitative questionnaire was distributed to workshop participants. The questionnaire elicited information on experiences and practices in building and maintaining consortia. This chapter reports on the numerous challenges and their possible solutions as identified by the workshop participants, as well as new opportunities offered by the network approach to genetic and genomic epidemiology.

AB - The Human Genome Epidemiology Network (HuGENet) recently launched a global network of consortia working on human genome epidemiology. This Network of Investigator Networks aims to create a resource to share information, offer methodologic support, generate inclusive overviews of studies conducted in specific fields, and to facilitate rapid confirmation of findings. In October 2005, HuGENet brought together representatives from established and emerging networks in order to share their experiences at a workshop in Cambridge, United Kingdom. In advance of the meeting, a qualitative questionnaire was distributed to workshop participants. The questionnaire elicited information on experiences and practices in building and maintaining consortia. This chapter reports on the numerous challenges and their possible solutions as identified by the workshop participants, as well as new opportunities offered by the network approach to genetic and genomic epidemiology.

KW - Genetic epidemiology

KW - Hugenet

KW - Human genome epidemiology

KW - Investigator networks

UR - https://www.scopus.com/pages/publications/84921258796

U2 - 10.1093/acprof:oso/9780195398441.003.0007

DO - 10.1093/acprof:oso/9780195398441.003.0007

M3 - Chapter

AN - SCOPUS:84921258796

SN - 9780195398441

BT - Human Genome Epidemiology

PB - Oxford University Press

ER -

Seminara D, Khoury MJ, O'brien TR, Manolio T, Gwinn M, Little J et al. The emergence of networks in human genome epidemiology: Challenges and opportunities. In Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press. 2010 doi: 10.1093/acprof:oso/9780195398441.003.0007

The emergence of networks in human genome epidemiology: Challenges and opportunities

Abstract

Keywords

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