The impact of extracorporeal membrane oxygenation on cerebral oxygen delivery during cardiac arrest: a case series

Emma Roellke; Sam Parnia; Jignesh Patel; Steven Friedman; Amanda Mengotto

doi:10.1016/j.resplu.2020.100068

The impact of extracorporeal membrane oxygenation on cerebral oxygen delivery during cardiac arrest: a case series

Emma Roellke
, Sam Parnia
, Jignesh Patel
, Steven Friedman
, Amanda Mengotto

Pulmonary and Critical Care

New York University
Albert Einstein College of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Aim: To describe the impact of extracorporeal membrane oxygenation (ECMO) assisted CPR (E-CPR) on cerebral oxygen delivery during in-hospital cardiac arrest (IHCA). Methods: Retrospective case series from a tertiary academic medical center. Regional cerebral oxygen saturation (rSO2) was measured continuously using cerebral oximetry in six patients who experienced IHCA. During CPR, the time of E-CPR initiation was recorded, and rSO2 values were subsequently analyzed for a period beginning 5 min before and ending 2.5 min after the initiation of E-CPR. Results: The average rSO₂ value in the 2.5 min period following E-CPR initiation increased by 20.8% as compared to the 5-min period before E-CPR initiation. Conclusions: ECMO can be employed in parallel with cerebral rSO2 monitoring during CPR for adult IHCA patients. E-CPR is associated with rapid and significant increases in brain oxygen delivery.

Original language	English
Article number	100068
Journal	Resuscitation Plus
Volume	5
DOIs	https://doi.org/10.1016/j.resplu.2020.100068
State	Published - Mar 2021

Keywords

Brain oxygen delivery
CPR
Cardiac arrest
ECMO
Ischemic brain injury
Resuscitation

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10.1016/j.resplu.2020.100068

Cite this

@article{37cdba07ae244de6a88582d594f9e692,

title = "The impact of extracorporeal membrane oxygenation on cerebral oxygen delivery during cardiac arrest: a case series",

abstract = "Aim: To describe the impact of extracorporeal membrane oxygenation (ECMO) assisted CPR (E-CPR) on cerebral oxygen delivery during in-hospital cardiac arrest (IHCA). Methods: Retrospective case series from a tertiary academic medical center. Regional cerebral oxygen saturation (rSO2) was measured continuously using cerebral oximetry in six patients who experienced IHCA. During CPR, the time of E-CPR initiation was recorded, and rSO2 values were subsequently analyzed for a period beginning 5 min before and ending 2.5 min after the initiation of E-CPR. Results: The average rSO2 value in the 2.5 min period following E-CPR initiation increased by 20.8\% as compared to the 5-min period before E-CPR initiation. Conclusions: ECMO can be employed in parallel with cerebral rSO2 monitoring during CPR for adult IHCA patients. E-CPR is associated with rapid and significant increases in brain oxygen delivery.",

keywords = "Brain oxygen delivery, CPR, Cardiac arrest, ECMO, Ischemic brain injury, Resuscitation",

author = "Emma Roellke and Sam Parnia and Jignesh Patel and Steven Friedman and Amanda Mengotto",

note = "Publisher Copyright: {\textcopyright} 2020 The Author(s)",

year = "2021",

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doi = "10.1016/j.resplu.2020.100068",

language = "English",

volume = "5",

journal = "Resuscitation Plus",

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T1 - The impact of extracorporeal membrane oxygenation on cerebral oxygen delivery during cardiac arrest

T2 - a case series

AU - Roellke, Emma

AU - Parnia, Sam

AU - Patel, Jignesh

AU - Friedman, Steven

AU - Mengotto, Amanda

PY - 2021/3

Y1 - 2021/3

N2 - Aim: To describe the impact of extracorporeal membrane oxygenation (ECMO) assisted CPR (E-CPR) on cerebral oxygen delivery during in-hospital cardiac arrest (IHCA). Methods: Retrospective case series from a tertiary academic medical center. Regional cerebral oxygen saturation (rSO2) was measured continuously using cerebral oximetry in six patients who experienced IHCA. During CPR, the time of E-CPR initiation was recorded, and rSO2 values were subsequently analyzed for a period beginning 5 min before and ending 2.5 min after the initiation of E-CPR. Results: The average rSO2 value in the 2.5 min period following E-CPR initiation increased by 20.8% as compared to the 5-min period before E-CPR initiation. Conclusions: ECMO can be employed in parallel with cerebral rSO2 monitoring during CPR for adult IHCA patients. E-CPR is associated with rapid and significant increases in brain oxygen delivery.

AB - Aim: To describe the impact of extracorporeal membrane oxygenation (ECMO) assisted CPR (E-CPR) on cerebral oxygen delivery during in-hospital cardiac arrest (IHCA). Methods: Retrospective case series from a tertiary academic medical center. Regional cerebral oxygen saturation (rSO2) was measured continuously using cerebral oximetry in six patients who experienced IHCA. During CPR, the time of E-CPR initiation was recorded, and rSO2 values were subsequently analyzed for a period beginning 5 min before and ending 2.5 min after the initiation of E-CPR. Results: The average rSO2 value in the 2.5 min period following E-CPR initiation increased by 20.8% as compared to the 5-min period before E-CPR initiation. Conclusions: ECMO can be employed in parallel with cerebral rSO2 monitoring during CPR for adult IHCA patients. E-CPR is associated with rapid and significant increases in brain oxygen delivery.

KW - Brain oxygen delivery

KW - CPR

KW - Cardiac arrest

KW - ECMO

KW - Ischemic brain injury

KW - Resuscitation

UR - https://www.scopus.com/pages/publications/85126187515

U2 - 10.1016/j.resplu.2020.100068

DO - 10.1016/j.resplu.2020.100068

M3 - Article

AN - SCOPUS:85126187515

SN - 2666-5204

VL - 5

JO - Resuscitation Plus

JF - Resuscitation Plus

M1 - 100068

ER -

The impact of extracorporeal membrane oxygenation on cerebral oxygen delivery during cardiac arrest: a case series

Abstract

Keywords

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