The intercalative binding between rivanol and DNA

Wen You Li; Jin Gou Xu; Xiang Qun Guo; Qing Zhi Zhu; Yi Bing Zhao

The intercalative binding between rivanol and DNA

Wen You Li
, Jin Gou Xu
, Xiang Qun Guo
, Qing Zhi Zhu
, Yi Bing Zhao

Office of the Dean SOMAS

Xiamen University

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Rivanol(RVN) binds to the double helical DNA with a high affinity. Strong hypochromism and appreciable red shifts in the absorption spectra can be observed when RVN binds to CT DNA. The results of absorption spectra, KI quenching studies, fluorescence polarization measurements, competitive binding studies, and thermal denaturation experiments suggested that the interaction between RVN and DNA be intercalative.

Original language	English
Pages (from-to)	309-312
Number of pages	4
Journal	Chinese Chemical Letters
Volume	8
Issue number	4
State	Published - 1997

Cite this

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title = "The intercalative binding between rivanol and DNA",

abstract = "Rivanol(RVN) binds to the double helical DNA with a high affinity. Strong hypochromism and appreciable red shifts in the absorption spectra can be observed when RVN binds to CT DNA. The results of absorption spectra, KI quenching studies, fluorescence polarization measurements, competitive binding studies, and thermal denaturation experiments suggested that the interaction between RVN and DNA be intercalative.",

author = "Li, \{Wen You\} and Xu, \{Jin Gou\} and Guo, \{Xiang Qun\} and Zhu, \{Qing Zhi\} and Zhao, \{Yi Bing\}",

year = "1997",

language = "English",

volume = "8",

pages = "309--312",

journal = "Chinese Chemical Letters",

issn = "1001-8417",

number = "4",

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TY - JOUR

T1 - The intercalative binding between rivanol and DNA

AU - Li, Wen You

AU - Xu, Jin Gou

AU - Guo, Xiang Qun

AU - Zhu, Qing Zhi

AU - Zhao, Yi Bing

PY - 1997

Y1 - 1997

N2 - Rivanol(RVN) binds to the double helical DNA with a high affinity. Strong hypochromism and appreciable red shifts in the absorption spectra can be observed when RVN binds to CT DNA. The results of absorption spectra, KI quenching studies, fluorescence polarization measurements, competitive binding studies, and thermal denaturation experiments suggested that the interaction between RVN and DNA be intercalative.

AB - Rivanol(RVN) binds to the double helical DNA with a high affinity. Strong hypochromism and appreciable red shifts in the absorption spectra can be observed when RVN binds to CT DNA. The results of absorption spectra, KI quenching studies, fluorescence polarization measurements, competitive binding studies, and thermal denaturation experiments suggested that the interaction between RVN and DNA be intercalative.

UR - https://www.scopus.com/pages/publications/0031517168

M3 - Article

AN - SCOPUS:0031517168

SN - 1001-8417

VL - 8

SP - 309

EP - 312

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 4

ER -

The intercalative binding between rivanol and DNA

Abstract

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