@inproceedings{0d9225229b144daaa0aa773396faadd1,
title = "The role of endogenous electrical fields in the maintenance of bone mass",
abstract = "An animal model of disuse osteoporosis is used to identify the specific mechanical strain components which are most effective for the maintenance of bone mass. The high-frequency characteristics and low amplitudes of this optimal mechanical signal implicate a mechanism of transduction dependent on the derivative of the strain. It is suggested that endogenous electric fields would satisfy this requirement. It is also shown that bone remodeling is sensitive to the exogenous induction of electric fields, and that the process demonstrates a distinct frequency and dose dependence.",
author = "McLeod, \{Kenneth J.\} and Rubin, \{Clinton T.\}",
year = "1990",
language = "English",
isbn = "0879425598",
series = "Proceedings of the Annual Conference on Engineering in Medicine and Biology",
publisher = "Publ by IEEE",
number = "pt 4",
pages = "1568--1569",
booktitle = "Biomedical Engineering Perspectives",
edition = "pt 4",
note = "Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society ; Conference date: 01-11-1990 Through 04-11-1990",
}