The role of pharmacists in tetanus management and prevention

Acute tetanus is a preventable disease that could be fatal if not immediately treated. Tetanospasmin, a neuromuscular exotoxin released by Clostridium tetani, causes generalized rigidity and spasms. It is imperative to admit patients to rule out other etiologies and provide appropriate medical interventions. For acute cases, pharmacists in ICUs could promote best practices and uses of medications, which include sedative hypnotics, neuromuscular blocking agents, and antibiotics. The most recent need for tetanus prophylaxis in the United States arose after a natural disaster, Hurricane Sandy. Pharmacists should continue to promote public health information and counsel patients to remain updated with their vaccinations.