Toward breast cancer resistance protein (BCRP) inhibitors: design, synthesis of a series of new simplified fumitremorgin C analogues

Guofeng Wu; Jiawang Liu; Lanrong Bi; Ming Zhao; Chao Wang; Michèle Baudy-Floc'h; Jingfang Ju; Shiqi Peng

doi:10.1016/j.tet.2007.04.045

Toward breast cancer resistance protein (BCRP) inhibitors: design, synthesis of a series of new simplified fumitremorgin C analogues

Guofeng Wu
, Jiawang Liu
, Lanrong Bi
, Ming Zhao
, Chao Wang
, Michèle Baudy-Floc'h
, Jingfang Ju
, Shiqi Peng

Pathology

Peking University
Capital Medical University
Université de Rennes

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

In this study, we report the design and synthesis of a series of new simplified fumitremorgin C analogues. The preliminary biological study indicated some of these simplified fumitremorgin C might be developed into breast cancer resistance inhibitors.

Original language	English
Pages (from-to)	5510-5528
Number of pages	19
Journal	Tetrahedron
Volume	63
Issue number	25
DOIs	https://doi.org/10.1016/j.tet.2007.04.045
State	Published - Jun 18 2007

Keywords

Breast cancer resistance protein inhibitors
Coupling
Enantioselective synthesis
Fumitremorgin C analogues
Racemization

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10.1016/j.tet.2007.04.045

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title = "Toward breast cancer resistance protein (BCRP) inhibitors: design, synthesis of a series of new simplified fumitremorgin C analogues",

abstract = "In this study, we report the design and synthesis of a series of new simplified fumitremorgin C analogues. The preliminary biological study indicated some of these simplified fumitremorgin C might be developed into breast cancer resistance inhibitors.",

keywords = "Breast cancer resistance protein inhibitors, Coupling, Enantioselective synthesis, Fumitremorgin C analogues, Racemization",

author = "Guofeng Wu and Jiawang Liu and Lanrong Bi and Ming Zhao and Chao Wang and Mich{\`e}le Baudy-Floc'h and Jingfang Ju and Shiqi Peng",

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T2 - design, synthesis of a series of new simplified fumitremorgin C analogues

AU - Wu, Guofeng

AU - Liu, Jiawang

AU - Bi, Lanrong

AU - Zhao, Ming

AU - Wang, Chao

AU - Baudy-Floc'h, Michèle

AU - Ju, Jingfang

AU - Peng, Shiqi

PY - 2007/6/18

Y1 - 2007/6/18

N2 - In this study, we report the design and synthesis of a series of new simplified fumitremorgin C analogues. The preliminary biological study indicated some of these simplified fumitremorgin C might be developed into breast cancer resistance inhibitors.

AB - In this study, we report the design and synthesis of a series of new simplified fumitremorgin C analogues. The preliminary biological study indicated some of these simplified fumitremorgin C might be developed into breast cancer resistance inhibitors.

KW - Breast cancer resistance protein inhibitors

KW - Coupling

KW - Enantioselective synthesis

KW - Fumitremorgin C analogues

KW - Racemization

UR - https://www.scopus.com/pages/publications/34248560759

U2 - 10.1016/j.tet.2007.04.045

DO - 10.1016/j.tet.2007.04.045

M3 - Article

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SN - 0040-4020

VL - 63

SP - 5510

EP - 5528

JO - Tetrahedron

JF - Tetrahedron

IS - 25

ER -

Toward breast cancer resistance protein (BCRP) inhibitors: design, synthesis of a series of new simplified fumitremorgin C analogues

Abstract

Keywords

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