Updated guidance on the management of COVID-19: From an american thoracic society/european respiratory society coordinated international task force (29 July 2020)

Chunxue Bai; Sanjay H. Chotirmall; Jordi Rello; George A. Alba; Leo C. Ginns; Jerry A. Krishnan; Robert Rogers; Elisabeth Bendstrup; Pierre Regis Burgel; James D. Chalmers; Abigail Chua; Kristina A. Crothers; Abhijit Duggal; Yeon Wook Kim; John G. Laffey; Carlos M. Luna; Michael S. Niederman; Ganesh Raghu; Julio A. Ramirez; Jordi Riera; Oriol Roca; Maximiliano Tamae-Kakazu; Antoni Torres; Richard R. Watkins; Miriam Barrecheguren; Mirko Belliato; Hassan A. Chami; Rongchang Chen; Gustavo A. Cortes-Puentes; Charles Delacruz; Margaret M. Hayes; Leo M.A. Heunks; Steven R. Holets; Catherine L. Hough; Sugeet Jagpal; Kyeongman Jeon; Takeshi Johkoh; May M. Lee; Janice Liebler; Gerry N. McElvaney; Ari Moskowitz; Richard A. Oeckler; Iñigo Ojanguren; Anthony O’regan; Mathias W. Pletz; Chin Kook Rhee; Marcus J. Schultz; Enrico Storti; Charlie Strange; Carey C. Thomson; Francesca J. Torriani; Xun Wang; Wim Wuyts; Tao Xu; Dawei Yang; Ziqiang Zhang; Kevin C. Wilson

doi:10.1183/16000617.0287-2020

Updated guidance on the management of COVID-19: From an american thoracic society/european respiratory society coordinated international task force (29 July 2020)

Chunxue Bai
, Sanjay H. Chotirmall
, Jordi Rello
, George A. Alba
, Leo C. Ginns
, Jerry A. Krishnan
, Robert Rogers
, Elisabeth Bendstrup
, Pierre Regis Burgel
, James D. Chalmers
, Abigail Chua
, Kristina A. Crothers
, Abhijit Duggal
, Yeon Wook Kim
, John G. Laffey
, Carlos M. Luna
, Michael S. Niederman
, Ganesh Raghu
, Julio A. Ramirez
, Jordi Riera

Oriol Roca, Maximiliano Tamae-Kakazu, Antoni Torres, Richard R. Watkins, Miriam Barrecheguren, Mirko Belliato, Hassan A. Chami, Rongchang Chen, Gustavo A. Cortes-Puentes, Charles Delacruz, Margaret M. Hayes, Leo M.A. Heunks, Steven R. Holets, Catherine L. Hough, Sugeet Jagpal, Kyeongman Jeon, Takeshi Johkoh, May M. Lee, Janice Liebler, Gerry N. McElvaney, Ari Moskowitz, Richard A. Oeckler, Iñigo Ojanguren, Anthony O’regan, Mathias W. Pletz, Chin Kook Rhee, Marcus J. Schultz, Enrico Storti, Charlie Strange, Carey C. Thomson, Francesca J. Torriani, Xun Wang, Wim Wuyts, Tao Xu, Dawei Yang, Ziqiang Zhang, Kevin C. Wilson

Pulmonary and Critical Care

Zhongshan Hospital
Shanghai Respiratory Research Institution
Nanyang Technological University
H.U. Vall d’Hebron
Vall d'Hebron Barcelona Hospital Campus
CHU de Nîmes
Harvard University
University of Illinois at Chicago
Aarhus University
Université Paris Cité
University of Dundee
University of Washington
Cleveland Clinic Foundation
Seoul National University
University of Galway
Universidad de Buenos Aires
Cornell University
University of Louisville
University Hospital Vall d'Hebron
Autonomous University of Barcelona
Michigan State University
Hospital Clínic de Barcelona
Northeastern Ohio Universities College of Medicine
Division of Infectious Diseases
IRCCS Fondazione Policlinico San Matteo - Pavia
American University of Beirut
Southern University of Science and Technology
Mayo Clinic Rochester, MN
Yale University
Beth Israel Deaconess Medical Center
Academic Medical Center
Oregon Health and Science University
Robert Wood Johnson University Hospital
Sungkyunkwan University
Kansai Rosai Hospital
University of Southern California
Royal College of Surgeons in Ireland
Friedrich Schiller University Jena
The Catholic University of Korea
Ospedale Maggiore
Medical University of South Carolina
Mt. Auburn Hospital
University of California at San Diego
Wuxi No.2 People's Hospital
KU Leuven
Qingdao University
Tongji Hospital Tongji University
Boston University

Research output: Contribution to journal › Review article › peer-review

94 Scopus citations

Abstract

Background: Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research. Methods: An International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70% agreement was necessary to make a consensus suggestion. Results: The Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder. Conclusions: The Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities.

Original language	English
Article number	200287
Pages (from-to)	1-15
Number of pages	15
Journal	European Respiratory Review
Volume	29
Issue number	157
DOIs	https://doi.org/10.1183/16000617.0287-2020
State	Published - Sep 30 2020

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10.1183/16000617.0287-2020

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Bai, C., Chotirmall, S. H., Rello, J., Alba, G. A., Ginns, L. C., Krishnan, J. A., Rogers, R., Bendstrup, E., Burgel, P. R., Chalmers, J. D., Chua, A., Crothers, K. A., Duggal, A., Kim, Y. W., Laffey, J. G., Luna, C. M., Niederman, M. S., Raghu, G., Ramirez, J. A., ... Wilson, K. C. (2020). Updated guidance on the management of COVID-19: From an american thoracic society/european respiratory society coordinated international task force (29 July 2020). European Respiratory Review, 29(157), 1-15. Article 200287. https://doi.org/10.1183/16000617.0287-2020

@article{b1a56d464726495bb4ece49733ea97cd,

title = "Updated guidance on the management of COVID-19: From an american thoracic society/european respiratory society coordinated international task force (29 July 2020)",

abstract = "Background: Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research. Methods: An International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70\% agreement was necessary to make a consensus suggestion. Results: The Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder. Conclusions: The Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities.",

author = "Chunxue Bai and Chotirmall, \{Sanjay H.\} and Jordi Rello and Alba, \{George A.\} and Ginns, \{Leo C.\} and Krishnan, \{Jerry A.\} and Robert Rogers and Elisabeth Bendstrup and Burgel, \{Pierre Regis\} and Chalmers, \{James D.\} and Abigail Chua and Crothers, \{Kristina A.\} and Abhijit Duggal and Kim, \{Yeon Wook\} and Laffey, \{John G.\} and Luna, \{Carlos M.\} and Niederman, \{Michael S.\} and Ganesh Raghu and Ramirez, \{Julio A.\} and Jordi Riera and Oriol Roca and Maximiliano Tamae-Kakazu and Antoni Torres and Watkins, \{Richard R.\} and Miriam Barrecheguren and Mirko Belliato and Chami, \{Hassan A.\} and Rongchang Chen and Cortes-Puentes, \{Gustavo A.\} and Charles Delacruz and Hayes, \{Margaret M.\} and Heunks, \{Leo M.A.\} and Holets, \{Steven R.\} and Hough, \{Catherine L.\} and Sugeet Jagpal and Kyeongman Jeon and Takeshi Johkoh and Lee, \{May M.\} and Janice Liebler and McElvaney, \{Gerry N.\} and Ari Moskowitz and Oeckler, \{Richard A.\} and I{\~n}igo Ojanguren and Anthony O{\textquoteright}regan and Pletz, \{Mathias W.\} and Rhee, \{Chin Kook\} and Schultz, \{Marcus J.\} and Enrico Storti and Charlie Strange and Thomson, \{Carey C.\} and Torriani, \{Francesca J.\} and Xun Wang and Wim Wuyts and Tao Xu and Dawei Yang and Ziqiang Zhang and Wilson, \{Kevin C.\}",

note = "Publisher Copyright: {\textcopyright} ERS 2020.",

year = "2020",

month = sep,

day = "30",

doi = "10.1183/16000617.0287-2020",

language = "English",

volume = "29",

pages = "1--15",

journal = "European Respiratory Review",

issn = "0905-9180",

number = "157",

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Bai, C, Chotirmall, SH, Rello, J, Alba, GA, Ginns, LC, Krishnan, JA, Rogers, R, Bendstrup, E, Burgel, PR, Chalmers, JD, Chua, A, Crothers, KA, Duggal, A, Kim, YW, Laffey, JG, Luna, CM, Niederman, MS, Raghu, G, Ramirez, JA, Riera, J, Roca, O, Tamae-Kakazu, M, Torres, A, Watkins, RR, Barrecheguren, M, Belliato, M, Chami, HA, Chen, R, Cortes-Puentes, GA, Delacruz, C, Hayes, MM, Heunks, LMA, Holets, SR, Hough, CL, Jagpal, S, Jeon, K, Johkoh, T, Lee, MM, Liebler, J, McElvaney, GN, Moskowitz, A, Oeckler, RA, Ojanguren, I, O’regan, A, Pletz, MW, Rhee, CK, Schultz, MJ, Storti, E, Strange, C, Thomson, CC, Torriani, FJ, Wang, X, Wuyts, W, Xu, T, Yang, D, Zhang, Z & Wilson, KC 2020, 'Updated guidance on the management of COVID-19: From an american thoracic society/european respiratory society coordinated international task force (29 July 2020)', European Respiratory Review, vol. 29, no. 157, 200287, pp. 1-15. https://doi.org/10.1183/16000617.0287-2020

Updated guidance on the management of COVID-19: From an american thoracic society/european respiratory society coordinated international task force (29 July 2020). / Bai, Chunxue; Chotirmall, Sanjay H.; Rello, Jordi et al.
In: European Respiratory Review, Vol. 29, No. 157, 200287, 30.09.2020, p. 1-15.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Updated guidance on the management of COVID-19

T2 - From an american thoracic society/european respiratory society coordinated international task force (29 July 2020)

AU - Bai, Chunxue

AU - Chotirmall, Sanjay H.

AU - Rello, Jordi

AU - Alba, George A.

AU - Ginns, Leo C.

AU - Krishnan, Jerry A.

AU - Rogers, Robert

AU - Bendstrup, Elisabeth

AU - Burgel, Pierre Regis

AU - Chalmers, James D.

AU - Chua, Abigail

AU - Crothers, Kristina A.

AU - Duggal, Abhijit

AU - Kim, Yeon Wook

AU - Laffey, John G.

AU - Luna, Carlos M.

AU - Niederman, Michael S.

AU - Raghu, Ganesh

AU - Ramirez, Julio A.

AU - Riera, Jordi

AU - Roca, Oriol

AU - Tamae-Kakazu, Maximiliano

AU - Torres, Antoni

AU - Watkins, Richard R.

AU - Barrecheguren, Miriam

AU - Belliato, Mirko

AU - Chami, Hassan A.

AU - Chen, Rongchang

AU - Cortes-Puentes, Gustavo A.

AU - Delacruz, Charles

AU - Hayes, Margaret M.

AU - Heunks, Leo M.A.

AU - Holets, Steven R.

AU - Hough, Catherine L.

AU - Jagpal, Sugeet

AU - Jeon, Kyeongman

AU - Johkoh, Takeshi

AU - Lee, May M.

AU - Liebler, Janice

AU - McElvaney, Gerry N.

AU - Moskowitz, Ari

AU - Oeckler, Richard A.

AU - Ojanguren, Iñigo

AU - O’regan, Anthony

AU - Pletz, Mathias W.

AU - Rhee, Chin Kook

AU - Schultz, Marcus J.

AU - Storti, Enrico

AU - Strange, Charlie

AU - Thomson, Carey C.

AU - Torriani, Francesca J.

AU - Wang, Xun

AU - Wuyts, Wim

AU - Xu, Tao

AU - Yang, Dawei

AU - Zhang, Ziqiang

AU - Wilson, Kevin C.

PY - 2020/9/30

Y1 - 2020/9/30

N2 - Background: Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research. Methods: An International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70% agreement was necessary to make a consensus suggestion. Results: The Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder. Conclusions: The Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities.

AB - Background: Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research. Methods: An International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70% agreement was necessary to make a consensus suggestion. Results: The Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder. Conclusions: The Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities.

UR - https://www.scopus.com/pages/publications/85092418767

U2 - 10.1183/16000617.0287-2020

DO - 10.1183/16000617.0287-2020

M3 - Review article

C2 - 33020069

AN - SCOPUS:85092418767

SN - 0905-9180

VL - 29

SP - 1

EP - 15

JO - European Respiratory Review

JF - European Respiratory Review

IS - 157

M1 - 200287

ER -

Updated guidance on the management of COVID-19: From an american thoracic society/european respiratory society coordinated international task force (29 July 2020)

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