Volumetric asymmetries of the human brain: Intellectual correlates

Volumetric measures of the brain and ventricles were derived from CT films and related to intellectual variables from the Wechsler Adult Intelligence Scale (WAIS). Subjects were patients referred for neurological examination for headache or somatic complaints, sometimes accompanied by anxiety or dysphoric affect (N = 41), for whom a comprehensive neurological work-up revealed no evidence of abnormality. The asymmetry of hemispheric volume (left minus right over total, times 100) was correlated (r = .57, p < .001) with Verbal IQ minus Performance IQ within subjects. No relationship was observed between total brain or hemispheric volumes and IQ scores. Brain and ventricular volumes were larger for the left hemisphere than the right.