Skip to main navigation Skip to search Skip to main content

When NMDA receptor conductances increase inter-spike interval variability

  • University of Bern

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

We analyze extensively the temporal properties of the train of spikes emitted by a simple model neuron as a function of the statistics of the synaptic input. In particular we focus on the asynchronous case, in which the synaptic inputs are random and uncorrelated. We show that the NMDA component acts as a non-stationary input that varies on longer time scales than the inter-spike intervals. In the subthreshold regime, this can increase dramatically the coefficient of variability (bringing it beyond one). The analysis provides also simple guidelines for searching parameters that maximize irregularity.

Original languageEnglish
Title of host publicationArtificial Neural Networks, ICANN 2002 - International Conference, Proceedings
EditorsJose R. Dorronsoro, Jose R. Dorronsoro
PublisherSpringer Verlag
Pages235-240
Number of pages6
ISBN (Electronic)3540440747
ISBN (Print)9783540440741
DOIs
StatePublished - 2002
Event2002 International Conference on Artificial Neural Networks, ICANN 2002 - Madrid, Spain
Duration: Aug 28 2002Aug 30 2002

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume2415 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference2002 International Conference on Artificial Neural Networks, ICANN 2002
Country/TerritorySpain
CityMadrid
Period08/28/0208/30/02

Fingerprint

Dive into the research topics of 'When NMDA receptor conductances increase inter-spike interval variability'. Together they form a unique fingerprint.

Cite this