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Whole-Genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates

  • Sherwood R. Casjens
  • , Emmanuel F. Mongodin
  • , Wei Gang Qiu
  • , John J. Dunn
  • , Benjamin J. Luft
  • , Claire M. Fraser-Liggett
  • , Steve E. Schutzer
  • University of Utah
  • University of Maryland, Baltimore
  • City University of New York
  • Brookhaven National Laboratory
  • Rutgers - The State University of New Jersey, New Brunswick

Research output: Contribution to journalComment/debate

67 Scopus citations

Abstract

Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. afzelii isolates ACA-1 and PKo and B. garinii isolates PBr and Far04.

Original languageEnglish
Pages (from-to)6995-6996
Number of pages2
JournalJournal of Bacteriology
Volume193
Issue number24
DOIs
StatePublished - Dec 2011

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