Isoflurane anesthesia therapy: A replacement for ECT in depressive disorders?

L. B. Greenberg; J. Gage; S. Vitkun; M. Fink

Isoflurane anesthesia therapy: A replacement for ECT in depressive disorders?

L. B. Greenberg
, J. Gage
, S. Vitkun
, M. Fink

Anesthesiology

Stony Brook University

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Isoflurane anesthesia therapy (IAT) has been suggested to have persistent antidepressant activity. In a replication trial, IAT was performed in six patients who had a recurrence of a severe depressive episode, previously treated with ECT. In 21 of 26 IAT sessions, an isoelectric electroencephalogram lasting between 5 and 12 min was recorded. Clinical antidepressant activity was not observed. It is concluded that IAT is not an effective replacement for ECT in the treatment of major depressive disorders.

Original language	English
Pages (from-to)	269-277
Number of pages	9
Journal	Convulsive Therapy
Volume	3
Issue number	4
State	Published - 1987

Cite this

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title = "Isoflurane anesthesia therapy: A replacement for ECT in depressive disorders?",

abstract = "Isoflurane anesthesia therapy (IAT) has been suggested to have persistent antidepressant activity. In a replication trial, IAT was performed in six patients who had a recurrence of a severe depressive episode, previously treated with ECT. In 21 of 26 IAT sessions, an isoelectric electroencephalogram lasting between 5 and 12 min was recorded. Clinical antidepressant activity was not observed. It is concluded that IAT is not an effective replacement for ECT in the treatment of major depressive disorders.",

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T2 - A replacement for ECT in depressive disorders?

AU - Greenberg, L. B.

AU - Gage, J.

AU - Vitkun, S.

AU - Fink, M.

PY - 1987

Y1 - 1987

N2 - Isoflurane anesthesia therapy (IAT) has been suggested to have persistent antidepressant activity. In a replication trial, IAT was performed in six patients who had a recurrence of a severe depressive episode, previously treated with ECT. In 21 of 26 IAT sessions, an isoelectric electroencephalogram lasting between 5 and 12 min was recorded. Clinical antidepressant activity was not observed. It is concluded that IAT is not an effective replacement for ECT in the treatment of major depressive disorders.

AB - Isoflurane anesthesia therapy (IAT) has been suggested to have persistent antidepressant activity. In a replication trial, IAT was performed in six patients who had a recurrence of a severe depressive episode, previously treated with ECT. In 21 of 26 IAT sessions, an isoelectric electroencephalogram lasting between 5 and 12 min was recorded. Clinical antidepressant activity was not observed. It is concluded that IAT is not an effective replacement for ECT in the treatment of major depressive disorders.

UR - https://www.scopus.com/pages/publications/0023489282

M3 - Article

AN - SCOPUS:0023489282

SN - 0749-8055

VL - 3

SP - 269

EP - 277

JO - Convulsive Therapy

JF - Convulsive Therapy

IS - 4

ER -

Isoflurane anesthesia therapy: A replacement for ECT in depressive disorders?

Abstract

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